One of the most significant factors is mobility, as greater mobility of an individual tends to give it greater migratory potential. There are a number of factors that affect the rate of gene flow between different populations. Immigration may also result in the addition of new genetic variants to the established gene pool of a particular species or population. Migration into or out of a population may be responsible for a marked change in allele frequencies. In population genetics, gene flow is the transfer of alleles or genes from one population to another. Freebase Rate this definition: 0.0 / 0 votes